Hello, Ryan!
This is definitely within our capabilities. We have constructed numerous custom acrylic enclosures for televisions, laboratory equipment, gaming consoles, and more! For all of these items, we laser cut ventilation holes as well as any holes for wires or disc insert and button access. All of these of products also come with a secure cam-lock with keys but we can omit that for you if it is unnecessary.
For this item, please send us a drawing or sketch of the custom acrylic enclosure for any holes for wires, buttons, and such. Please include the measurements for those as well as the overall measurements.
Thank you!